X-Ray Crystallography

The X-Ray Crystallography Lab uses diffraction methods to determine high-precision three-dimensional solid-state structures of crystalline organic, inorganic and biological molecules and to identify polycrystalline materials.

  • High-resolution (to 0.78 Å ) small-molecule, protein and qualitative powder diffraction data collection accomplished using dual area-detector configuration with shared high-flux Bruker MicroStar microfocus Cu rotating anode x-ray source that is comparable to a second-generation synchrotron
  • Cu data collection uses either Bruker Apex II CCD detector equipped with Helios multilayer optics or Bruker Platinum 135 CCD area detector equipped with high-brilliance Helios multilayer optics
  • High-resolution (>0.78 Å) small-molecule data collection using a Bruker Apex CCD area detector, graphite-monochromated Mo radiation with a monoCap beam collimator and a sealed tube x-ray source
  • Structure determinations for microcrystals or poorly-diffracting small-molecule samples
Victor Day, Ph.D.
Malott Hall, room 6044
785-864-4347
vwday@ku.edu

LINKS TO LAB WEBSITES

Biochemistry & Protein Science

Bioinformatics & Modeling

Cross-Disciplinary

Materials Characterization

Molecular Structures

Translational Biology

EVENTS
Ability to set up 24 NMR experiments at one time and eliminate periodic user intervention
Screen up to 100,000 compounds in two days for endpoint assays
Next-generation genome sequencing
Near-infrared and bioluminescence imaging instrumentation to track gene of interest and/or tumor growth
Expertise in the design and stability of various pharmaceutical dosage forms
More than 40 computational chemistry software programs and databases
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