Stuart Macdonald, Ph.D.

Director, Genomics and Bioinformatics Lab
Primary office:
785-864-5362
Haworth Hall, room 4043


Stuart Macdonald is the Director of the Genomics and Bioinformatics Laboratory and an Associate Professor in the Molecular Biosciences Department at the University of Kansas.  

Dr. Macdonald joined KU in 2006 as an Assistant Professor.  Prior to joining KU, Stuart was an undergraduate at the University of Oxford (1994-1997), a PhD student also at Oxford (1997-2000), a postdoctoral fellow at University College London (2000-2001), and a postdoctoral fellow at the University of California - Irvine (2001-2006).

Research Interests
Genetics of complex traits
Genome biology
Drosophila quantitative genetics

 

Representative Publications

Find all articles by Stuart Macdonald on PubMed and Google Scholar.

Macdonald SJ, Long AD. Fine scale structural variants distinguish the genomes of Drosophila melanogaster and D. pseudoobscura. Genome Biol. 2006; 7(7):R67.

Macdonald SJ, Pastinen T, Genissel A, Cornforth TW, Long AD. A low-cost open-source SNP genotyping platform for association mapping applications. Genome Biol. 2005; 6(12):R105.

Macdonald SJ, Pastinen T, Long AD. The effect of polymorphisms in the Enhancer of split gene complex on bristle number variation in a large wild-caught cohort of Drosophila melanogaster. Genetics 2005; 171(4):1741-56.

Macdonald SJ, Long AD. Prospects for identifying functional variation across the genome. Proc. Natl. Acad. Sci. USA 2005; 102(Suppl):6614-21.

Macdonald SJ, Long AD. Identifying signatures of selection at the Enhancer of split neurogenic gene complex in Drosophila. Mol. Biol. Evol. 2005; 22(3):607-19.

Macdonald SJ, Long AD. A potential regulatory polymorphism upstream of hairy is not associated with bristle number variation in wild-caught Drosophila. Genetics 2004; 167(4):2127-31.

List of publications available at PubMed
Macdonald SJ, Long AD. Fine scale structural variants distinguish the genomes of Drosophila melanogaster and D. pseudoobscura. Genome Biol. 2006; 7(7):R67.
 
Macdonald SJ, Pastinen T, Genissel A, Cornforth TW, Long AD. A low-cost open-source SNP genotyping platform for association mapping applications. Genome Biol. 2005; 6(12):R105.
 
Macdonald SJ, Pastinen T, Long AD. The effect of polymorphisms in the Enhancer of split gene complex on bristle number variation in a large wild-caught cohort of Drosophila melanogaster. Genetics 2005; 171(4):1741-56.
 
Macdonald SJ, Long AD. Prospects for identifying functional variation across the genome. Proc. Natl. Acad. Sci. USA 2005; 102(Suppl):6614-21.
 
Macdonald SJ, Long AD. Identifying signatures of selection at the Enhancer of split neurogenic gene complex in Drosophila. Mol. Biol. Evol. 2005; 22(3):607-19.
 
Macdonald SJ, Long AD. A potential regulatory polymorphism upstream of hairy is not associated with bristle number variation in wild-caught Drosophila. Genetics 2004; 167(4):2127-31.

LINKS TO LAB WEBSITES

Biochemistry & Protein Science

Bioinformatics & Modeling

Cross-Disciplinary

Materials Characterization

Molecular Structures

Translational Biology

EVENTS
Ability to set up 24 NMR experiments at one time and eliminate periodic user intervention
Screen up to 100,000 compounds in two days for endpoint assays
Next-generation genome sequencing
Near-infrared and bioluminescence imaging instrumentation to track gene of interest and/or tumor growth
Expertise in the design and stability of various pharmaceutical dosage forms
More than 40 computational chemistry software programs and databases
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