Medicinal Chemistry

The Synthetic Chemical Biology Laboratory is a university-based drug discovery facility with a state-of-the-art infrastructure for pharmaceutical research. The Core provides medicinal, synthetic, and combinatorial chemistry support for Core B (IDAD) and COBRE investigators.

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  • Preparing targeted libraries for screening and lead optimization
  • Synthesizing organic compounds on various scales (from mg to multi-gram)
  • Synthesize custom peptides
  • Assisting COBRE investigators, if requested, in the design of novel ligands and in the development of practical synthetic routes
Chamani Perera, Ph.D
Core Director
Shankel Structural Biology Center
785-864-6114 (office) or 785-864-6095 (lab)


Biochemistry & Protein Science

Bioinformatics & Modeling


Materials Characterization

Molecular Structures

Translational Biology

Ability to set up 24 NMR experiments at one time and eliminate periodic user intervention
Screen up to 100,000 compounds in two days for endpoint assays
Next-generation genome sequencing
Near-infrared and bioluminescence imaging instrumentation to track gene of interest and/or tumor growth
Expertise in the design and stability of various pharmaceutical dosage forms
More than 40 computational chemistry software programs and databases
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