Medicinal Chemistry

The Synthetic Medicinal Chemistry Laboratory is a university-based drug discovery facility with a state-of-the-art infrastructure for pharmaceutical research. The Core provides medicinal, synthetic, and combinatorial chemistry support for Core B (HTS) and COBRE investigators.

More Details
  • Preparing targeted libraries for screening and lead optimization
  • Synthesizing organic compounds on various scales (from mg to multi-gram)
  • Providing extracts from natural products
  • Assisting COBRE investigators, if requested, in the design of novel ligands and in the development of practical synthetic routes
Steven Rogers, Ph.D
Shankel Structural Biology Center, room 1070
785-864-3942
sarogers@ku.edu

LINKS TO LAB WEBSITES

Biochemistry & Protein Science

Bioinformatics & Modeling

Cross-Disciplinary

Materials Characterization

Molecular Structures

Translational Biology

EVENTS
Ability to set up 24 NMR experiments at one time and eliminate periodic user intervention
Screen up to 100,000 compounds in two days for endpoint assays
Next-generation genome sequencing
Near-infrared and bioluminescence imaging instrumentation to track gene of interest and/or tumor growth
Expertise in the design and stability of various pharmaceutical dosage forms
More than 40 computational chemistry software programs and databases
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