High throughput screening

The High Throughput Screening (HTS) lab is dedicated to providing exceptional services in advancing drug discovery research initiatives, as well as assistance in preparing grant applications. The lab utilizes several chemical libraries of compounds to identify novel chemical entities that target a biological system of interest.

Infectious Disease Assay Development

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  • Discussion on screening goals, assays and instrument compatibility
  • Primary assay optimization and data analysis including protocols and selection of controls
  • Validation screening of a small library with a robust optimized assay
  • Screening the complete library of compounds Data analysis and storage
  • Secondary screen development and/or screening of primary hits
  • Plating various dilutions of compounds and siRNA libraries
Anuradha Roy, Ph.D
Shankel Structural Biology Center


Biochemistry & Protein Science

Bioinformatics & Modeling


Materials Characterization

Molecular Structures

Translational Biology

Ability to set up 24 NMR experiments at one time and eliminate periodic user intervention
Screen up to 100,000 compounds in two days for endpoint assays
Next-generation genome sequencing
Near-infrared and bioluminescence imaging instrumentation to track gene of interest and/or tumor growth
Expertise in the design and stability of various pharmaceutical dosage forms
More than 40 computational chemistry software programs and databases
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