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Helping Faculty Researchers and External Collaborators Transform Basic Research into New Drug Therapies

Improved understanding and treatment of disease, prevention, diagnosis and control therapies relies on the identification of the biological pathways that lead to disease development. Transforming these basic research findings into new drug therapies —by targeting and selecting the most promising leads- is the goal of the drug discovery research at the University of Kansas.

The process of drug discovery is complex and involves multiple disciplines. Biomedical investigators working with the core research labs have access to state-of-art equipment and experienced lab personnel to expedite their drug discovery efforts.
 

Core Lab and Research Center Drug Discovery Activities

Assay Development/HTS Chemical Synthesis
High Throughput Screening (HTS)
Immunology
Microscopy and Analytical Imaging
Molecular Probes
Chemical Methodolgoies and Library Development
Specialized Chemistry
Medicinal Chemistry
Molecular Probes
Target Discovery Compound Profiling/Biological Testing
Analytical Proteomics
High Throughput Screening
Geonomics and Bioinformatics
Genome Sequencing
Immunology
Mass Spectrometry
Microscopy and Analytical Imaging
Molecular Graphics and Modeling
Molecular Probes
Nuclear Magnetic Resonance
X-Ray Crystallography
Analytical Proteomics
BIO Center
Biological Irradiation
Biomolecular NMR
​Experimental and Preclinical Imaging
Immunology
Mass Spectrometry
Molecular Probes
Nuclear Magnetic Resonance
Protein Production
Protein Structure
Solid State NMR
X-Ray Crystallography

LINKS TO LAB WEBSITES

Biochemistry & Protein Science

Bioinformatics & Modeling

Cross-Disciplinary

Materials Characterization

Molecular Structures

Translational Biology

EVENTS
Ability to set up 24 NMR experiments at one time and eliminate periodic user intervention
Screen up to 100,000 compounds in two days for endpoint assays
Next-generation genome sequencing
Near-infrared and bioluminescence imaging instrumentation to track gene of interest and/or tumor growth
Expertise in the design and stability of various pharmaceutical dosage forms
More than 40 computational chemistry software programs and databases
KU Today