Biomolecular NMR

The Biomolecular NMR Lab provides NMR resources and technical expertise for study of macromolecular structure, function and dynamics in solution. Its capabilities include determining high resolution structures, biological macromolecules, elucidation and structural mapping of protein-protein, protein-nucleic acid, protein-peptide, protein-drug interactions, and studies of the dynamics of proteins and their complexes in solution.

  • 1D-4D NMR Data Collection
  • Data processing, analysis, and interpretation
  • Structure determination
  • Heteronuclear relaxation measurements and data analysis
  • H/D exchange measurements by NMR
  • NMR titration measurement
  • Protein-ligand interaction studies
  • Training for new instrument users
  • Consultation on proposal preparation
Minli Xing
Shankel Structural Biology Center, room 1011
785-864-3277
mxing@ku.edu

LINKS TO LAB WEBSITES

Biochemistry & Protein Science

Bioinformatics & Modeling

Cross-Disciplinary

Materials Characterization

Molecular Structures

Translational Biology

EVENTS
Ability to set up 24 NMR experiments at one time and eliminate periodic user intervention
Screen up to 100,000 compounds in two days for endpoint assays
Next-generation genome sequencing
Near-infrared and bioluminescence imaging instrumentation to track gene of interest and/or tumor growth
Expertise in the design and stability of various pharmaceutical dosage forms
More than 40 computational chemistry software programs and databases
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