BIO Center Select Publications

For a complete list of publications, go to the BIO Center website.

2009
​Duerfeldt AS, Blagg BS. Hydrating for resistance to radicicol. ACS Chem Biol. 2009 Apr 17; 4 (4): 245-7. Review. PMID: 19371133.

Amolins MW, Blagg BS. Natural product inhibitors of Hsp90: potential leads fordrug discovery. Mini Rev Med Chem. 2009 Feb; 9(2): 140-52. Review. PMID: 19200020; PMCID: PMC2659174.

Donnelly A, Blagg BS. Novobiocin and additional inhibitors of the Hsp90Cterminal nucleotide-binding pocket. Curr Med Chem. 2008; 15(26): 2702-17. Review. PMID: 18991631.

Hadden MK, Blagg BS. Dimeric approaches to anti-cancer chemotherapeutics. Anticancer Agents Med Chem. 2008 Oct; 8(7): 807-16. Review. PMID: 18855582; PMCID: PMC2679389.

Tongiani S, Ozeki T, Stella VJ. Sulfobutyl ether-alkyl ether mixed cyclodextrin derivatives with enhanced inclusion ability. J Pharm Sci. 2009 Apr 30. [Epub ahead of print] PMID: 19408308.

Mudra DR, Borchardt RT. Absorption barriers in the rat intestinal mucosa. 3: Effects of polyethoxylated solubilizing agents on drug permeation and metabolism. J Pharm Sci. 2009 Jul 31. [Epub ahead of print] PMID: 19650119.

Ouyang H, Andersen TE, Chen W, Nofsinger R, Steffansen B, Borchardt RT. A comparison of the effects of p-glycoprotein inhibitors on the blood-brain barrier permeation of cyclic prodrugs of an opioid peptide (DADLE). J Pharm Sci. 2009 Jun; 98(6): 2227-36. PMID: 18855917.

Ouyang H, Chen W, Andersen TE, Steffansen B, Borchardt RT. Factors that restrict intestinal cell permeation of cyclic prodrugs of an opioid peptide (DADLE): Part II. Role of metabolic enzymes in the intestinal mucosa. J Pharm Sci. 2009 Jan; 98(1): 349-61. PMID: 18537150.

Ouyang H, Chen W, Andersen TE, Steffansen B, Borchardt RT. Factors that restrict the intestinal cell permeation of cyclic prodrugs of an opioid peptide(DADLE): Part I. Role of efflux transporters in the intestinal mucosa. J Pharm Sci. 2009 Jan; 98(1): 337-48. PMID: 18537149.

2008
Donnelly AC, Mays JR, Burlison JA, Nelson JT, Vielhauer G, Holzbeierlein J, Blagg BS. The design, synthesis, and evaluation of coumarin ring derivatives of the novobiocin scaffold that exhibit antiproliferative activity. J Org Chem. 2008 Nov 21; 73(22): 8901-20. Epub 2008 Oct 22. PMID: 18939877; PMCID: PMC2646372.

Chittasupho C, Xie SX, Baoum A, Yakovleva T, Siahaan TJ, Berkland CJ. ICAM-1 targeting of doxorubicin-loaded PLGA nanoparticles to lung epithelial cells. Eur J Pharm Sci. 2009 May 12; 37(2): 141-50. Epub 2009 Feb 27. PMID: 19429421.

El-Gendy N, Berkland C. Combination chemotherapeutic dry powder aerosols via controlled nanoparticle agglomeration. Pharm Res. 2009 Jul; 26(7): 1752-63. Epub 2009 May 5. PMID: 19415471.

Aillon KL, Xie Y, El-Gendy N, Berkland CJ, Forrest ML. Effects of nanomaterial physicochemical properties on in vivo toxicity. Adv Drug Deliv Rev. 2009 Jun 21; 61(6): 457-66. Epub 2009 Apr 20. PMID: 19386275.

Plumley C, Gorman EM, El-Gendy N, Bybee CR, Munson EJ, Berkland C. Nifedipine nanoparticle agglomeration as a dry powder aerosol formulation strategy. Int J Pharm. 2009 Mar 18; 369(1-2): 136-43. Epub 2008 Oct 25. PMID: 19015016.

Bailey MM, Gorman EM, Munson EJ, Berkland C. Pure insulin nanoparticle agglomerates for pulmonary delivery. Langmuir. 2008 Dec 2; 24(23): 13614-20. PMID: 18959432; PMCID: PMC2649680.
Bailey MM, Berkland CJ. Nanoparticle formulations in pulmonary drug delivery. Med Res Rev. 2009 Jan; 29(1):1 96-212. PubMed PMID: 18958847.

Singh M, Berkland C, Detamore MS. Strategies and applications for incorporating physical and chemical signal gradients in tissue engineering. Tissue Eng Part B Rev. 2008 Dec; 14(4): 341-66. PMID: 18803499.

Singh M, Morris CP, Ellis RJ, Detamore MS, Berkland C. Microsphere-based seamless scaffolds containing macroscopic gradients of encapsulated factors for tissue engineering. Tissue Eng Part C Methods. 2008 Dec; 14(4): 299-309. PMID: 18795865.

Peek LJ, Roberts L, Berkland C. Poly(D,L-lactide-co-glycolide) nanoparticle agglomerates as carriers in dry powder aerosol formulation of proteins. Langmuir. 2008 Sep 2; 24(17): 9775-83. Epub 2008 Aug 5. PMID: 18680321.
Huang M, Berkland C. Controlled release of repifermin from polyelectrolyte complexes stimulates endothelial cell proliferation. J Pharm Sci. 2009 Jan; 98(1): 268-80. PMID: 18425807.


LINKS TO LAB WEBSITES

Biochemistry & Protein Science

Bioinformatics & Modeling

Cross-Disciplinary

Materials Characterization

Molecular Structures

Translational Biology

EVENTS
Ability to set up 24 NMR experiments at one time and eliminate periodic user intervention
Screen up to 100,000 compounds in two days for endpoint assays
Next-generation genome sequencing
Near-infrared and bioluminescence imaging instrumentation to track gene of interest and/or tumor growth
Expertise in the design and stability of various pharmaceutical dosage forms
More than 40 computational chemistry software programs and databases
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